Brazil-Bolivia: The Roboré Accord of March 29, 1958 placed the long-disputed Isla Suárez/Ilha de Guajará-Mirim, a fluvial island on the Río Mamoré, between the two towns of Guajará-Mirim (Brazil) and Guayaramerin (Bolivia), under Bolivian administration but did not resolve the sovereignty disputeBrazil-Colombia: Contraband smuggling (narcotics and arms), illegal migration, trafficking in animals, plants, lumber, illegal exploitation of mineral resources, Colombian (FARC) insurgent incursions in the area remain problematic issues.Brazil-Uruguay: The uncontested boundary dispute between Brazil and Uruguay over over Arroyo de la Invernada triangle and sovereignty over Isla Brasilera leaves the tripoint with Argentina in question. Smuggling of firearms and narcotics continues to be an issue along the Uruguay-Brazil border.Brazil-Venezuela: Colombian-organized illegal narcotics and paramilitary activities penetrate Brazil's border region with Venezuela.

Refugees country of origin: 261,441 (Venezuela) (economic and political crisis; includes Venezuelans who have claimed asylum, are recognized as refugees, or received alternative legal stay) (2020)

IDPs: 21,000

Stateless persons: 14 (mid-year 2021)

a significant transit and destination country for cocaine; most of the cocaine enters Brazil from neighboring producing countries Bolivia, Colombia, and Peru then goes to West Africa and Europe, but an increasing percentage feeds substantial domestic drug consumption; second-largest consumer of cocaine hydrochloride and cocaine-derivative products in the world